Optimal Control of Evolutionary Dynamics

نویسندگان

  • Raj Chakrabarti
  • Herschel Rabitz
  • George McLendon
چکیده

Elucidating the fitness measures optimized during the evolution of complex biological systems is a major challenge in evolutionary theory. We present experimental evidence and an analytical framework demonstrating how biochemical networks exploit optimal control strategies in their evolutionary dynamics. Optimal control theory explains a striking pattern of extremization in the redox potentials of electron transport proteins, assuming only that their fitness measure is a control objective functional with bounded controls.

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تاریخ انتشار 2008